Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA5-16464 targets Calcitonin in IHC (P) applications and shows reactivity with mouse, Non-human primate, Rat, Canine, Equine, Human, Ovine, and Porcine samples. Staining of formalin-fixed tissues requires boiling in 10mM citrate buffer pH 6.0 for 10-20 minutes followed by cooling at RT for 20 minutes.
The PA5-16464 immunogen is a synthetic peptide from human calcitonin.
Calcitonin is a 32 amino acid peptide which can be demonstrated in C cells of the normal and hyperplastic thyroid. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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