Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA5-19852 targets KSHV ORF8 in indirect ELISA, WB applications and shows reactivity with Human samples.
The PA5-19852 immunogen is synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.
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Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi’s sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman’s disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Kaposi's Sarcoma Virus; Kaposi's sarcoma-associated herpesvirus
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