Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: A431, H1299, HeLa, HepG2.
Predicted reactivity: Mouse (100%), Rat (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
HIPK3 is a serine/threonine kinase involved in signal transduction, cellular communication, and multidrug resistance of tumors and plays a role in the phosphorylation of FADD. HIPK3 negatively regulates apoptosis by promoting FADD phosphorylation. This kinase enhances androgen receptor-mediated transcription, and may act as a transcriptional corepressor for NK homeodomain transcription factors.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Androgen receptor-interacting nuclear protein kinase; ANPK; Fas-interacting serine/threonine-protein kinase; FIST; Homeodomain-interacting protein kinase 3; Homolog of protein kinase YAK1; RP1-8L15.1
Gene Aliases: DYRK6; FIST3; HIPK3; PKY; YAK1
UniProt ID: (Human) Q9H422
Entrez Gene ID: (Human) 10114
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