Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Peptide sequence: LRDGASRRGE SMQPNRRADD NATIRVTNLS EDTRETDLQE LFRPFGSISR
Sequence homology: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: eIF-3 RNA-binding subunit; eIF-3-delta; eiF3 delta; eIF3 p42; eIF3 p44; eIF3g; Eukaryotic translation initiation factor 3 RNA-binding subunit; Eukaryotic translation initiation factor 3 subunit 4; Eukaryotic translation initiation factor 3 subunit G; eukaryotic translation initiation factor 3, subunit 4 (delta); eukaryotic translation initiation factor 3, subunit 4 (delta, 44 kDa); eukaryotic translation initiation factor 3, subunit 4 (delta, 44kD); eukaryotic translation initiation factor 3 subunit p42; translation initiation factor eIF3-p44
Gene Aliases: 44kDa; D0Jmb4; eIF3-delta; EIF3-P42; eIF3-p44; EIF3G; Eif3p42; EIF3S4; p44; TU-189B2
UniProt ID: (Human) O75821, (Mouse) Q9Z1D1
Entrez Gene ID: (Human) 8666, (Mouse) 53356
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support