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Immunogen sequence: EPNPAGKKKK YLKAALYVGD LDPDVTEDML YKKFRPAGPL RFTRICRDPV TRSPLGYGYV NFRFPADAEW ALNTMNFDLI NGKPFRLMWS QPDDRLRKSG VGNIFIKNLD KSIDNR
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
PABPC5 encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. PABPC5 is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PABP-5; poly(A) binding protein, cytoplasmic 5; Polyadenylate-binding protein 5
Gene Aliases: PABP5; PABPC5
UniProt ID: (Human) Q96DU9
Entrez Gene ID: (Human) 140886
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