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Immunogen sequence: LNVTPTVRPD ADQMTKIPFF DDVGAVTLQY FDTLFQRDNL QKSQFFKGLP KVLPKLPKRV IVQRILPCLT SEFVNPDMVP FVLPNVLLIA EECTKEEYVK LILPELGPVF KQQEPIQILL IFLQKMDLLL TKTPPDEIKN S
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
SCYL2 is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. SCYL2 is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. SCYL2 may also regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Coated vesicle-associated kinase of 104 kDa; SCY1-like 2; SCY1-like protein 2; SCY1-like, kinase-like 2
Gene Aliases: CVAK104; KIAA1360; SCYL2
UniProt ID: (Human) Q6P3W7
Entrez Gene ID: (Human) 55681
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