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Immunogen sequence: RIPFFVKPPN AEPLVAPQLL PSSSLEVVPE AAQNNPGEEV TETAGEGSES IIKEETEENS HCDANTEMQQ ILTRVRQNFG KINVVPQFSG DDLVPV
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 68%.
GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (PubMed:26203195). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Autoantigen NGP-1; guanine nucleotide binding protein-like 2 (nucleolar); novel nucleolar guanosine 5'-triphosphate binding protein autoantigen; nucleolar G-protein gene 1; Nucleolar GTP-binding protein 2; nucleolar GTPase; nucleostemin-2
Gene Aliases: GNL2; HUMAUANTIG; Ngp-1; NGP1; Nog2; Nug2
UniProt ID: (Human) Q13823
Entrez Gene ID: (Human) 29889
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