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Immunogen sequence: SGRKMATEGG VSPPGASAGG GPSTAAHIEP PTQEVAEAPP AASSLSLPVI GSAAERGFFE AERDNADRGA AGGAGVESWA DAIEFVPGQP YRGRWVASA
Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 58%.
The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Probable E3 ubiquitin-protein ligase makorin-3; RING finger protein 63; RING-type E3 ubiquitin transferase makorin-3; Zinc finger protein 127
Gene Aliases: CPPB2; D15S9; MKRN3; RNF63; ZFP127; ZNF127
UniProt ID: (Human) Q13064
Entrez Gene ID: (Human) 7681
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