Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: APNGFKQHGN PHLYHSQGKG SYKHDRVVPQ SRASAQIISS SKSQILAPGE KITGKVKSDN GTGYDTDSSQ DSRDRGNSCD SSSKSRNR
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 66%.
Tight junction-associated protein that is involved in the survival of auditory hair cells and hearing. Maybe by modulating the barrier properties and mechanical stability of tight junctions. Has no peptidase activity (PubMed:14715245). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Inactive ubiquitin carboxyl-terminal hydrolase 53; Inactive ubiquitin-specific peptidase 53; ubiquitin specific protease 53; ubiquitin specific proteinase 53; USP53
Gene Aliases: KIAA1350; USP53
UniProt ID: (Human) Q70EK8
Entrez Gene ID: (Human) 54532
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