Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MNQVHVGGSL AVLGGKLYVS GGYDNTFELS DVVEAYDPET RAWSVVGRLP EPTFWHGSVS IFRQFMPQTF SGGRGFELD
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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