Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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Immunogen sequence: AMPGFIAKRLC PQLIIVPPNF DKYRAVSKEV KEILADYDPN FMAMSLDEAY LNITKHLEER QNWPEDKRRY FIKMGSSVEN DNPGKEVNKL SEHERSISPL LFEESPSDVQ PPGDPFQVNF EEQNNPQILQ NS
Highest antigen sequence identity to the following orthologs - mouse 82%, rat 80%.
External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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