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Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.
NIPAL4 acts as a Mg(2+) transporter and can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+). NIPAL4 may also be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. The NIPAL4 gene likely encodes a membrane receptor. Mutations in the NIPAL4 gene have been associated with autosomal recessive congenital ichthyosis. Diseases associated with NIPAL4 include Ichthyosis, Congenital, Autosomal Recessive 6 and Autosomal Recessive Congenital Ichthyosis.
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