Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 3
Positive Control: Neuro2A, NIH-3T3, Raw264.7, C2C12, MCF-7, MDA-MB-231
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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