Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
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Immunogen sequence: QLQSTPRPLQ EEVPVVRPLQ PRAARGGAGG GAQSQGVKEP GPEAGLHTAP LQERRIGGVF QDLVVNTRQD MKHVKDSKTG SEGTVVQLLA NHFRVISRPQ WVAYKYNVDY KPDIEDGNLR TILLDQHRRK FGERHIFDGN SLLLSRPLKE RRVEWLSTTK DKNIVKITVE FSKELTPTSP DCLRYYNILF RRTFKLLDFE QVGRNYYTKK KAIQLYRHGT SLEIWLGYVT SVLQYENSIT LCADVSHKLL RIETAYDFIK RTSAQAQTGN IREEVTNKLI G; Positive Samples: Mouse testis, Rat testis; Cellular Location: Cytoplasm
PIWI-L3 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. Recent studies have shown that overexpression of PIWI-L3 (as well as other PIWI-like proteins) are potential biomarkers for astrocytic glioma, meningioma, and other cancers.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
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