|Flow Cytometry (Flow)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Western Blot (WB)||See 3 publications below|
|Immunofluorescence (IF)||See 1 publications below|
|Flow Cytometry (Flow)||See 7 publications below|
|Immunohistochemistry (IHC)||See 1 publications below|
|Tested Species reactivity||Bovine, Human|
|Published species reactivity||Artificial Control , Human Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||The antiserum was produced against a chemically synthesized peptide corresponding to N-terminus of cleavage site (214/215) of human PARP.|
|Storage buffer||PBS, pH 7.2, with BSA|
|Contains||0.1% sodium azide|
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); ADPRT; ADPRT 1; ADPRT1; ARTD1; NAD(+) ADP-ribosyltransferase 1; pADPRT-1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; Poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL
Gene Aliases: ADPRT; ADPRT 1; ADPRT1; ARTD1; BOS_15645; pADPRT-1; PARP; PARP-1; PARP1; PPOL
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