Various cellular responses are regulated by the second messengers cAMP and cGMP. Phosphodiesterases, such as PDE10A, eliminate cAMP- and cGMP-mediated intracellular signaling by hydrolyzing the cyclic nucleotide to the corresponding nucleoside 5-prime monophosphate (Fujishige et al., 2000 [PubMed 10998054]).
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Protein Aliases: 5'-cyclic phosphodiesterase 10A; cAMP and cAMP-inhibited cGMP 3'; cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A; dJ416F21.1 (phosphodiesterase 10A); HSPDE10A; phosphodiesterase 10A1 (PDE10A1); phosphodiesterase 10A7 (PDE10A7)
Gene Aliases: ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A; PDE10A19
UniProt ID: (Human) Q9Y233
Entrez Gene ID: (Human) 10846