MA5-17152 targets PLK1 in FACS, IHC, pep-ELISA, and WB applications and shows reactivity with Human and Mouse samples.
The MA5-17152 immunogen is purified recombinant fragment of human PLK1 (amino acids: 331-508) expressed in E. Coli.
MA5-17152 detects PLK1 which has a predicted molecular weight of approximately 68kDa.
Polo-like kinase 1 (Plk1) plays key roles in many aspects of mitosis. Suppression of Plk1 by p21(Waf1) is responsible for p53-dependent protection against adriamycin-induced caspase-independent mitotic death.
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Protein Aliases: cell cycle regulated protein kinase; PLK-1; polo (Drosophia)-like kinase; polo like kinase; Polo-like kinase 1; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase PLK1; STPK13
Gene Aliases: PLK; PLK1; STPK13