This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
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MA5-15667 targets ZBTB16 in indirect ELISA, IF and WB applications and shows reactivity with Human samples.
The MA5-15667 immunogen is purified recombinant fragment of human ZBTB16 expressed in E. Coli.
MA5-15667 detects ZBTB16 which has a predicted molecular weight of approximately 74kDa.
This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.
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Protein Aliases: promyelocytic leukaemia zinc finger; Promyelocytic leukemia zinc finger protein; Zinc finger and BTB domain-containing protein 16; Zinc finger protein 145; zinc finger protein 145 (Kruppel-like, expressed in promyelocytic leukemia); Zinc finger protein PLZF
Gene Aliases: PLZF; ZBTB16; ZNF145
UniProt ID: (Human) Q05516
Entrez Gene ID: (Human) 7704
Molecular Function: C2H2 zinc finger transcription factor