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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 21 and 207 of Human PPIF|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31061 targets PPIF in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31061 immunogen is recombinant fragment corresponding to a region within amino acids 21 and 207 of Human PPIF.
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cyclophilin 3; cyclophilin D; cyclophilin F; Cyp-D; CYP3; mitochondrial; mitochondrial cyclophilin; peptidyl-prolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase F; peptidyl-prolyl cis-trans isomerase, mitochondrial; PPIase F; rotamase F
Cyp-D; CyP-M; CYP3; CypD; PPIF