This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
700902 has been successfully used in immunofluorescence analysis of PSD95 in human motor neurons derived from iPSCs.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
PDS-95 (Postsynaptic density-95) also known as Disks large homolog 4 is a protein that in humans is encoded by the DLG4 gene. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. PSDs were originally identified as an electron-dense region at the membrane of a postsynaptic neuron. PSD-95 interacts with NMDA receptor subunit and potassium channels and is required for synaptic plasticity associated with NMDA receptor signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: discs large homolog 4; Disks large homolog 4; Dlg4; Post Synaptic Density; post-synaptic density protein 95; Postsynaptic density protein 95; PSD-95; PSD95; SAP-90; SAP90; Synapse Associated Protein 95 kDa; Synapse-associated protein 90; synapse-associated protein SAP90; Tax interaction protein 15
Gene Aliases: DLG4; Dlgh4; PSD95; SAP-90; SAP90