|Immunohistochemistry (Frozen) (IHC (F))||1:10-1:500|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:500|
|Western Blot (WB)||1:500-1:1000|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human, Mouse, Rat|
|Published species reactivity||Chicken|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to residues 269-279 of the human and mouse PTCH protein.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Suggested positive control: antigen standard for PTCH1 (transient overexpression lysate).
Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BCNS; FLJ26746; FLJ42602; HPE7; mesenchymal dysplasia; NBCCS; Patched 1; patched homolog 1; patched homolog 2; patched protein; patched-like protein; Protein patched homolog 1; PTC; PTC1; PTCH; PTCH protein +12b; PTCH protein +4'; PTCH protein -10; PTCH protein -3,4,5; Ptch1 protein +12b; PTCH11; RP11-435O5.3
Gene Aliases: A230106A15Rik; BCNS; HPE7; mes; NBCCS; PTC; PTC1; PTCH; PTCH1; PTCH11; Ptch2
Molecular Function: receptor
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.