|Immunohistochemistry (Paraffin) (IHC (P))||1:10|
|Immunohistochemistry (IHC)||See 6 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant protein corresponding to C-terminal region of human perforin|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12469 targets Perforin in IHC (P) applications and shows reactivity with Human samples.
The MA5-12469 immunogen is recombinant protein corresponding to C-terminal region of human perforin.
Perforin is a potent cytolytic pore-forming protein. It is a specific marker of functionally active cytotoxic T-lymphocytes (CTLs) and natural killer (NK) cells. Perforin is a key effector mechanisms in T cell-mediated cytotoxicity. It mediates cytolysis of target cells by membrane damage and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytolysin; lymphocyte pore forming protein; Lymphocyte pore-forming protein; P1; perforin 1 (pore forming protein); Perforin-1; PFP
Gene Aliases: FLH2; HPLH2; P1; PFN1; PFP; PRF1
UniProt ID: (Human) P14222
Entrez Gene ID: (Human) 5551
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