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|Tested species reactivity||Fruit fly, Human, Mouse, Non-human primate, Rat, Xenopus, Yeast|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic phosphopeptide corresponding to residues surrounding pTyr15 of human cdc2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with CDK4, CDK6 or CDK7.
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
cdc2; cdc2 kinase; Cdk1-PA; cell cycle controller CDC2; cell cycle p34 CDC2 kinase protein; cell division control; cell division control protein 2 homolog; Cell division control protein 2 homolog 1; cell division control protein 2-A; cell division cycle 2 homolog A; cell division cycle 2 like; cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division cycle control protein 2a; cell division protein kinase 1; cell division protein kinase 1-A; CG5363-PA; cyclin dependent kinase; cyclin-dependent kinase; Cyclin-dependent kinase 1; cyclin-dependent kinase 1-A; OTTHUMP00000019660; p34 protein kinase; p34 protein kinase 1; protein 2
cdc; 5363; cdc-2; CDC2; cdc2-a; CDC28A; Cdc2a; cdc2Dm; cdc2x1.1; CDCDm; Cdk-1; CDK1; cdk1-a; CDK1/CDC2; CDKN1; CG5363; Dcdc2; dCdk1; Dm cdc2; DmCdc2; DmCdk1; Dmel\CG5363; Dmel_CG5363; group 4; l(2)31Eh; p34<CDC2>; P34CDC2; PSTAIR; xcdc2