Phospho-DOK2 (Tyr139) Polyclonal Antibody detects endogenous levels of DOK2 only when phosphorylated at Tyr139.
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Dok-R; Dok-related protein; Downstream of tyrosine kinase 2; FRIP; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; p56 dok-2; p56(dok-2)
Gene Aliases: DOK2; DokR; Frip; p56DOK; p56dok-2