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Product Details
PA5-95677
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr1007 of rat KCC2 conjugated to KLH |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
~0.25 mg/mL |
Purification |
Antigen Affinity Chromatography |
Storage buffer |
10mM HEPES, pH 7.5, with 100µg/mL BSA, 50% glycerol, 0.15M NaCl |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2807479 |
Product Specific Information
Antigen Affinity Purified from Pooled Serum
Target Information
Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Electroneutral potassium-chloride cotransporter 2; Furosemide-sensitive K-Cl cotransporter; K-Cl cotransporter 2; KCC 2; KCC2a variant 1; KCC2a-S25 variant 1; KCC2b variant 2; mKCC2; Neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; S12A5; Solute carrier family 12 member 5; solute carrier family 12, member 5
Gene Aliases: KCC2; Kiaa1176; mKIAA1176; Slc12a5
UniProt ID: (Mouse) Q91V14, (Rat) Q63633
Entrez Gene ID: (Mouse) 57138, (Rat) 171373
Molecular Function:
secondary carrier transporter
transport
ion transport
potassium ion transport
chloride transport
chemical synaptic transmission
learning
organic cation transport
ammonium transport
multicellular organism growth
thermosensory behavior
response to drug
intracellular pH reduction
transmembrane transport
ammonium transmembrane transport
cation transmembrane transport
chloride transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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