Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-29457 detects MARCKS from mouse, rat, human samples.
PA1-29457 has been successfully used in Western blot applications.
The PA1-29457 immunogen is: This antibody was developed against synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser152 and phospho Ser 153 of MARCKS (Rat).
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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