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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||This antibody was developed against synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser152 and phospho Ser 153 of MARCKS (Rat).|
|Storage buffer||HEPES buffered saline, pH 7.5, with 100µg/ml BSA, 50% glycerol|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-29457 detects MARCKS from mouse, rat, human samples.
PA1-29457 has been successfully used in Western blot applications.
The PA1-29457 immunogen is: This antibody was developed against synthetic phosphopeptide corresponding to amino acids residues surrounding the phospho-Ser152 and phospho Ser 153 of MARCKS (Rat).
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
80K protein; 80K-L; FLJ14368; FLJ90045; MACS; myristoylated alanine-rich C-kinase substrate; Myristoylated alanine-rich protein kinase C substrate; myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L); phosphomyristin; PKCSL; PRKCSL; protein kinase C substrate 80 kDa protein; protein kinase C substrate, 80 kDa protein, light chain
80K-L; KINC; MACS; MARCKS; PKCSL; PRKCSL