|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Peptide sequence around phosphorylation site of Serine738/Serine 742 (E-K-S(p)-F-R-R-S(p)-V-V) derived from Human PKD1/2/3/PKC mu|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
A suggested positive control for Western blot is A549 cells.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC mu is one of the PKC family members. The protein is a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.
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Protein Aliases: DKFZP586E0820; EPK2; HSPC187; mu; nPKC-D1; NPKC-D2; nPKC-mu; nPKC-NU; nu; PKC-NU; PKD3; PRKCN; PRKD2; protein kinase C; Protein kinase C mu type; Protein kinase C nu type; protein kinase C, mu; protein kinase C, nu; Protein kinase D; Protein kinase D2; Protein kinase EPK2; protein-serine/threonine kinase; Serine/threonine-protein kinase D1; Serine/threonine-protein kinase D2; Serine/threonine-protein kinase D3
Gene Aliases: 4930557O20Rik; 5730497N19Rik; AI325941; EPK2; HSPC187; nPKC-D1; nPKC-D2; nPKC-mu; nPKC-NU; PKC-MU; PKC-NU; PKCM; Pkcnu; PKD; PKD1; PKD2; PKD3; PRKCM; PRKCN; PRKD1; PRKD2; PRKD3; RGD1308054
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