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The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human RPS6 that contains serines 235 and 236. The sequence is conserved in mouse and rat.
Antigen affinity chromatography
Dulbecco's PBS, pH 7.3, with 1mg/ml BSA, 50% glycerol
0.05% sodium azide
Ribosomal protein 6 (RPS6) is a component of the 40S ribosomal subunit belonging to S6E family of ribosomal proteins. RPS6 is a key substrate for kinases, and is phosphorylated by growth factors and mitogens during in cell growth and cell division. Phosporylation in RPS6 is well regulated, and the different phosphorylation sites are highly conserved. Major phosphorylation sites of RPS6 include Ser 235, 236, 240, and 244.
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Protein Aliases: 40S ribosomal protein S6; Phosphoprotein NP33; ribosomal protein S6; RPS6; RS6; Small ribosomal subunit protein eS6