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|Tested species reactivity||Bovine, Nematode, Fruit fly, Human, Mollusca, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of c-Met that contains tyrosine 1365. The sequence is conserved in human, mouse and rat.|
|Storage buffer||Dulbecco's PBS, pH 7.3, with 50% glycerol, 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The c-Met oncogene was originally isolated from a chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a trans-membrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
c-Met; EC 22.214.171.124; hepatocyte growth factor receptor; Hepatocyte growth factor receptor precursor; HGF receptor; HGF receptor c-Met; HGF-SF receptor; HGF/SF receptor; kinase EC 126.96.36.199; Met proto- oncogene tyros; Met proto- oncogene tyrosine kinase; met proto-oncogene tyrosine kinase; proto-oncogene c-Met; scatter factor receptor; SF receptor; tyrosine-protein kinase Met
AI838057; AUTS9; c-Met; DFNB97; HGF; HGFR; MET; Par4; RCCP2