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MA5-15524 targets REG1A in indirect ELISA, IF and IHC applications and shows reactivity with Human samples.
The MA5-15524 immunogen is purified recombinant fragment of human REG1A fused with hIgGFc tag expressed in HEK293 cell line.
MA5-15524 detects REG1A which has a predicted molecular weight of approximately 19kDa.
This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; Lithostathine; lithostathine 1 alpha; Lithostathine-1-alpha; MGC12447; Pancreatic stone protein; pancreatic stone protein, secretory; Pancreatic thread protein; protein-X; PSP; PTP; REG; REG-1-alpha; regenerating islet-derived mouse homolog 1; Regenerating islet-derived protein 1-alpha; Regenerating protein I alpha; regeneration protein, lithostatin, pancreatic stone protein
Gene Aliases: ICRF; LITHOST; P19; PSP; PSPS; PSPS1; PTP; RATLITHOST; RATRGPI; REG; Reg1; REG1A; Rgp1; RGPI
UniProt ID: (Human) P05451, (Rat) P10758
Entrez Gene ID: (Human) 5967, (Rat) 24714
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