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Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), colon adenocarcinoma (B), liver carcinoma (C), skin carcinoma (D), breast ductal tumor (E) and brain tumor (F) using RSK1 monoclonal antibody (Product # MA5-15341) followed with DAB staining.
|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Purified recombinant fragment of human RSK1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15341 targets RSK1 in IHC and WB applications and shows reactivity with Human samples.
The MA5-15341 immunogen is purified recombinant fragment of human RSK1 expressed in E. Coli.
This gene encodes a member of the RSK family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
90 kDa ribosomal protein S6 kinase 1; dJ590P13.1 (ribosomal protein S6 kinase, 90kD, polypeptide 1); HU-1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; MAPKAPK-1a; MAPKAPK1A; p90-RSK 1; p90RSK1; p90S6K; ribosomal protein S6 kinase alpha 1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal S6 kinase 1; RPS6KA1; RSK; RSK-1; RSK1; S6K-alpha 1; S6K-alpha-1
HU-1; MAPKAPK1A; p90Rsk; RPS6KA1; RSK; RSK1