|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Immunoprecipitation (IP)||2 µg|
|Western Blot (WB)||1:500 - 1:1000|
|Tested Species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Recombinant full-length human Rap1|
|Storage buffer||PBS with 30% glycerol, 1mg/ml BSA|
|Contains||0.05% sodium azide|
Western blot analysis of MA1-013 detects an ~21kDa protein.
Rap1 is part of the Ras family of GTPases and is encoded by Rap1a and Rap1b. Rap1 cycles between two conformational states depending on whether GDP bound (active form) or GTP bound (inactive form) and primarily regulates multiple integrin-dependent processes such as morphogenesis, cell-cell adhesion and tumor invasion. Rap1 may also regulate proliferation, differentiation and survival through multiple downstream effectors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C21KG; G-22K; GTP-binding protein smg p21A; GTP-binding protein SMG-P21A; Ras-related protein Krev-1; Ras-related protein Rap-1A
Gene Aliases: AI848598; C21KG; G-22K; KREV-1; KREV1; RAP1; RAP1A; SMGP21
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