Product References
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Journal of molecular medicine (Berlin, Germany)
Zhang Y,Chen X,Wang Q,Du C,Lu W,Yuan H,Zhang Z,Li D,Ling X,Ren X,Zhao Y,Su Q,Xing Z,Qin Y,Yang X,Shen Y,Wu H,Qi Y
Wed Dec 01 00:00:00 UTC 2021
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Journal of molecular medicine (Berlin, Germany)
Zhang Y,Chen X,Wang Q,Du C,Lu W,Yuan H,Zhang Z,Li D,Ling X,Ren X,Zhao Y,Su Q,Xing Z,Qin Y,Yang X,Shen Y,Wu H,Qi Y
Wed Dec 01 00:00:00 UTC 2021
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Journal of molecular medicine (Berlin, Germany)
Zhang Y,Chen X,Wang Q,Du C,Lu W,Yuan H,Zhang Z,Li D,Ling X,Ren X,Zhao Y,Su Q,Xing Z,Qin Y,Yang X,Shen Y,Wu H,Qi Y
Wed Dec 01 00:00:00 UTC 2021
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Journal of molecular medicine (Berlin, Germany)
Zhang Y,Chen X,Wang Q,Du C,Lu W,Yuan H,Zhang Z,Li D,Ling X,Ren X,Zhao Y,Su Q,Xing Z,Qin Y,Yang X,Shen Y,Wu H,Qi Y
Wed Dec 01 00:00:00 UTC 2021
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Journal of molecular medicine (Berlin, Germany)
Zhang Y,Chen X,Wang Q,Du C,Lu W,Yuan H,Zhang Z,Li D,Ling X,Ren X,Zhao Y,Su Q,Xing Z,Qin Y,Yang X,Shen Y,Wu H,Qi Y
Wed Dec 01 00:00:00 UTC 2021
Hyper-SUMOylation of SMN induced by SENP2 deficiency decreases its stability and leads to spinal muscular atrophy-like pathology.
Journal of molecular medicine (Berlin, Germany)
Zhang Y,Chen X,Wang Q,Du C,Lu W,Yuan H,Zhang Z,Li D,Ling X,Ren X,Zhao Y,Su Q,Xing Z,Qin Y,Yang X,Shen Y,Wu H,Qi Y
Wed Dec 01 00:00:00 UTC 2021
Dual SMN inducing therapies can rescue survival and motor unit function in symptomatic Δ7SMA mice.
Neurobiology of disease
Kray KM,McGovern VL,Chugh D,Arnold WD,Burghes AHM
Mon Nov 01 00:00:00 UTC 2021
Intragenic complementation of amino and carboxy terminal SMN missense mutations can rescue Smn null mice.
Human molecular genetics
McGovern VL,Kray KM,Arnold WD,Duque SI,Iyer CC,Massoni-Laporte A,Workman E,Patel A,Battle DJ,Burghes AHM
Sun Nov 01 00:00:00 UTC 2020
Mild SMN missense alleles are only functional in the presence of SMN2 in mammals.
Human molecular genetics
Iyer CC,Corlett KM,Massoni-Laporte A,Duque SI,Madabusi N,Tisdale S,McGovern VL,Le TT,Zaworski PG,Arnold WD,Pellizzoni L,Burghes AHM
Mon Oct 01 00:00:00 UTC 2018
Mild SMN missense alleles are only functional in the presence of SMN2 in mammals.
Human molecular genetics
Iyer CC,Corlett KM,Massoni-Laporte A,Duque SI,Madabusi N,Tisdale S,McGovern VL,Le TT,Zaworski PG,Arnold WD,Pellizzoni L,Burghes AHM
Mon Oct 01 00:00:00 UTC 2018
Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study.
Annals of clinical and translational neurology
Kolb SJ,Coffey CS,Yankey JW,Krosschell K,Arnold WD,Rutkove SB,Swoboda KJ,Reyna SP,Sakonju A,Darras BT,Shell R,Kuntz N,Castro D,Iannaccone ST,Parsons J,Connolly AM,Chiriboga CA,McDonald C,Burnette WB,Werner K,Thangarajh M,Shieh PB,Finanger E,Cudkowicz ME,McGovern MM,McNeil DE,Finkel R,Kaye E,Kingsley A,Renusch SR,McGovern VL,Wang X,Zaworski PG,Prior TW,Burghes AH,Bartlett A,Kissel JT
Mon Feb 01 00:00:00 UTC 2016
Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study.
Annals of clinical and translational neurology
Kolb SJ,Coffey CS,Yankey JW,Krosschell K,Arnold WD,Rutkove SB,Swoboda KJ,Reyna SP,Sakonju A,Darras BT,Shell R,Kuntz N,Castro D,Iannaccone ST,Parsons J,Connolly AM,Chiriboga CA,McDonald C,Burnette WB,Werner K,Thangarajh M,Shieh PB,Finanger E,Cudkowicz ME,McGovern MM,McNeil DE,Finkel R,Kaye E,Kingsley A,Renusch SR,McGovern VL,Wang X,Zaworski PG,Prior TW,Burghes AH,Bartlett A,Kissel JT
Mon Feb 01 00:00:00 UTC 2016
SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical Trials.
PloS one
Zaworski P,von Herrmann KM,Taylor S,Sunshine SS,McCarthy K,Risher N,Newcomb T,Weetall M,Prior TW,Swoboda KJ,Chen KS,Paushkin S
Mon Aug 08 00:00:00 UTC 2016
SMN Protein Can Be Reliably Measured in Whole Blood with an Electrochemiluminescence (ECL) Immunoassay: Implications for Clinical Trials.
PloS one
Zaworski P,von Herrmann KM,Taylor S,Sunshine SS,McCarthy K,Risher N,Newcomb T,Weetall M,Prior TW,Swoboda KJ,Chen KS,Paushkin S
Mon Aug 08 00:00:00 UTC 2016
Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA.
Human molecular genetics
Iyer CC,McGovern VL,Murray JD,Gombash SE,Zaworski PG,Foust KD,Janssen PM,Burghes AH
Sun Nov 01 00:00:00 UTC 2015
Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA.
Human molecular genetics
Iyer CC,McGovern VL,Murray JD,Gombash SE,Zaworski PG,Foust KD,Janssen PM,Burghes AH
Sun Nov 01 00:00:00 UTC 2015
SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA.
Human molecular genetics
McGovern VL,Iyer CC,Arnold WD,Gombash SE,Zaworski PG,Blatnik AJ,Foust KD,Burghes AH
Thu Oct 01 00:00:00 UTC 2015
SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA.
Human molecular genetics
McGovern VL,Iyer CC,Arnold WD,Gombash SE,Zaworski PG,Blatnik AJ,Foust KD,Burghes AH
Thu Oct 01 00:00:00 UTC 2015
Detection of survival motor neuron protein in buccal cells through electrochemiluminescence-based assay.
Assay and drug development technologies
Steinkellner H,Etzler J,Gmeiner BM,Laccone F
Wed Apr 01 00:00:00 UTC 2015
Detection of survival motor neuron protein in buccal cells through electrochemiluminescence-based assay.
Assay and drug development technologies
Steinkellner H,Etzler J,Gmeiner BM,Laccone F
Wed Apr 01 00:00:00 UTC 2015
Evaluation of SMN protein, transcript, and copy number in the biomarkers for spinal muscular atrophy (BforSMA) clinical study.
PloS one
Crawford TO,Paushkin SV,Kobayashi DT,Forrest SJ,Joyce CL,Finkel RS,Kaufmann P,Swoboda KJ,Tiziano D,Lomastro R,Li RH,Trachtenberg FL,Plasterer T,Chen KS
Mon Sep 10 00:00:00 UTC 2012
Evaluation of SMN protein, transcript, and copy number in the biomarkers for spinal muscular atrophy (BforSMA) clinical study.
PloS one
Crawford TO,Paushkin SV,Kobayashi DT,Forrest SJ,Joyce CL,Finkel RS,Kaufmann P,Swoboda KJ,Tiziano D,Lomastro R,Li RH,Trachtenberg FL,Plasterer T,Chen KS
Mon Sep 10 00:00:00 UTC 2012
Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses.
PloS one
Kobayashi DT,Olson RJ,Sly L,Swanson CJ,Chung B,Naryshkin N,Narasimhan J,Bhattacharyya A,Mullenix M,Chen KS
Wed Apr 25 00:00:00 UTC 2012
Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses.
PloS one
Kobayashi DT,Olson RJ,Sly L,Swanson CJ,Chung B,Naryshkin N,Narasimhan J,Bhattacharyya A,Mullenix M,Chen KS
Wed Apr 25 00:00:00 UTC 2012
Utility of survival motor neuron ELISA for spinal muscular atrophy clinical and preclinical analyses.
PloS one
Kobayashi DT,Olson RJ,Sly L,Swanson CJ,Chung B,Naryshkin N,Narasimhan J,Bhattacharyya A,Mullenix M,Chen KS
Wed Apr 25 00:00:00 UTC 2012