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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:1,000-1:6,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:300-1:1200 | - |
Immunohistochemistry (PFA fixed) (IHC (PFA)) |
1:300-1:1,200 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
1D2C8 |
Immunogen |
SOX10 Fusion Protein Ag23191 (267-466 aa encoded by BC002824) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: GKPHIDFGN VDIGEISHEV MSNMETFDVA ELDQYLPPNG HPGHVSSYSA AGYGLGSALA VASGHSAWIS KPPGVALPTV SPPGVDAKAQ VKTETAGPQG PPHYTDQPST SQIAYTSLSL PHYGSAFPSI SRPQFDYSDH QPSGPYYGHS GQASGLYSAF SYMGPSQRPL YTAISDPSPS GPQSHSPTHW EQPVYTTLSR P (267-466 aa encoded by BC002824)
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dominant megacolon, mouse, human homolog of; MGC15649; SRY; SRY (sex determining region Y)-box 10; SRY box 10; SRY-related HMG-box gene 10; Transcription factor SOX-10
Gene Aliases: DOM; PCWH; SOX10; WS2E; WS4; WS4C
UniProt ID: (Human) P56693
Entrez Gene ID: (Human) 6663
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