OriGene

SYP Monoclonal Antibody (OTI5H2), TrueMAB™

Product Image Gallery

SYP Antibody in Immunocytochemistry (ICC/IF) — Anti-SYP mouse monoclonal antibody (TA506530) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SYP(RC208972).

SYP Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SYP (RC208972, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SYP. Positive lysates LY401102 (100 µg) and LC401102 (20 µg) can be purchased separately from OriGene.

Product Details

TA506530

Applications	Tested Dilution	Publications
Western Blot (WB)	1:200-1:2,000	-
Immunocytochemistry (ICC/IF)	1:100	-

Product Specifications
Species Reactivity	Dog, Human
Host/Isotype	Mouse / IgG1
Class	Monoclonal
Type	Antibody
Clone	OTI5H2
Immunogen	Full length human recombinant protein of human SYP produced in HEK293T cell. View antigen
Conjugate	Unconjugated
Form	liquid
Concentration	1 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS with 1% BSA, 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles

Target Information

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.