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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 82 and 399 of Human TIF1 alpha|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-30286 targets TIF1 alpha in WB applications and shows reactivity with Human samples.
The PA5-30286 immunogen is recombinant fragment corresponding to a region within amino acids 82 and 399 of Human TIF1 alpha.
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
E3 ubiquitin-protein ligase TRIM24; hTIF1; PTC6; RING finger protein 82; RNF82; TF1A; TIF1; TIF1-alpha; TIF1A; TIF1ALPHA; transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; tripartite motif-containing 24
hTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA; TRIM24