TMEFF2 may be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation.
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Protein Aliases: cancer/testis antigen family 120, member 2; CT120.2; HPP1; Hyperplastic polyposis protein 1; TENB2; TMEFF2; tomoregulin; Tomoregulin-2; TPEF; TR-2; transmembrane protein TENB2; Transmembrane protein with EGF-like and two follistatin-like domains; transmembrane protein with EGF-like and two follistatin-like domains 2
Gene Aliases: CT120.2; HPP1; TENB2; TMEFF2; TPEF; TR; TR-2; UNQ178/PRO204
UniProt ID: (Human) Q9UIK5
Entrez Gene ID: (Human) 23671