Product References
Effect of LSKL peptide on thrombospondin 1-mediated transforming growth factor β signal activation and liver regeneration after hepatectomy in an experimental model.
The British journal of surgery
Kuroki H,Hayashi H,Nakagawa S,Sakamoto K,Higashi T,Nitta H,Hashimoto D,Chikamoto A,Beppu T,Baba H
MA5-13385 was used in western blot to test if a leucine-serine-lysine-leucine peptide promotes liver regeneration.
Mon Jun 01 00:00:00 EDT 2015
HGF regulates the activation of TGF-β1 in rat hepatocytes and hepatic stellate cells.
Journal of cellular physiology
Narmada BC,Chia SM,Tucker-Kellogg L,Yu H
MA5-13385 was used in ELISA to study the mechanism of HGF-regulated TGF-beta1 activation in hepatocytes and stellate cells and the significance for hepatic fibrosis
Fri Feb 01 00:00:00 EST 2013
Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress.
Molecular and cellular biology
Zhao Y,Wang S,Sorenson CM,Teixeira L,Dubielzig RR,Peters DM,Conway SJ,Jefcoate CR,Sheibani N
MA5-13385 was used in western blot to study the role of oxidative stress in the mechanism by which Cyp1b1 mediates regulation of the trabecular meshwork by periostin
Fri Nov 01 00:00:00 EDT 2013
Inflammatory cytokine-specific alterations in retinal endothelial cell function.
Microvascular research
Palenski TL,Sorenson CM,Sheibani N
MA5-13385 was used in western blot to study the effects of the inflammatory mediators TNF-alpha and IL-1beta on the function of retinal endothelial cells and the implications for diabetic retinopathy
Sun Sep 01 00:00:00 EDT 2013
Long-term gene therapy with thrombospondin 2 inhibits TGF-β activation, inflammation and angiogenesis in chronic allograft nephropathy.
PloS one
Daniel C,Vogelbacher R,Stief A,Grigo C,Hugo C
MA5-13385 was used in immunohistochemistry to study TGF-beta activation, inflammation and angiogenesis following long-term thrombospondin-2 gene therapy in a model of chronic allograft nephropathy
Mon Mar 02 00:00:00 EST 2015
A fibronectin-independent mechanism of collagen fibrillogenesis in adult liver remodeling.
Gastroenterology
Moriya K,Bae E,Honda K,Sakai K,Sakaguchi T,Tsujimoto I,Kamisoyama H,Keene DR,Sasaki T,Sakai T
MA5-13385 was used in western blot to study collagen fibrillogenesis during wound healing process
Sun May 01 00:00:00 EDT 2011
Expression of ADAMTS1 in endothelial cells is induced by shear stress and suppressed in sprouting capillaries.
Journal of cellular physiology
Hohberg M,Knöchel J,Hoffmann CJ,Chlench S,Wunderlich W,Alter A,Maroski J,Vorderwülbecke BJ,Da Silva-Azevedo L,Knudsen R,Lehmann R,Fiedorowicz K,Bongrazio M,Nitsche B,Hoepfner M,Styp-Rekowska B,Pries AR,Zakrzewicz A
MA5-13385 was used in western blot to study the shear stress-dependent expression of ADAMTS1 and its role in regulating angiogenesis
Tue Feb 01 00:00:00 EST 2011
The myc-miR-17~92 axis blunts TGF{beta} signaling and production of multiple TGF{beta}-dependent antiangiogenic factors.
Cancer research
Dews M,Fox JL,Hultine S,Sundaram P,Wang W,Liu YY,Furth E,Enders GH,El-Deiry W,Schelter JM,Cleary MA,Thomas-Tikhonenko A
MA5-13385 was used in western blot to study the role of clusterin downregulation in promoting angiogenesis and tumor growth
Fri Oct 15 00:00:00 EDT 2010
Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors.
Molecular cancer
Olsson A,Björk A,Vallon-Christersson J,Isaacs JT,Leanderson T
MA5-13385 was used in western blot to study the effect of the anti-angiogenic compound Tasquinimod on thrombospondin-1 expression in human prostate cancer cells
Mon May 17 00:00:00 EDT 2010
Morphine modulation of thrombospondin levels in astrocytes and its implications for neurite outgrowth and synapse formation.
The Journal of biological chemistry
Ikeda H,Miyatake M,Koshikawa N,Ochiai K,Yamada K,Kiss A,Donlin MJ,Panneton WM,Churchill JD,Green M,Siddiqui AM,Leinweber AL,Crews NR,Ezerskiy LA,Rendell VR,Belcheva MM,Coscia CJ
MA5-13385 was used in western blot to study the modulation of thrombospondin-1 levels in astrocytes by morphine and its implications for neurite outgrowth and synapse formation
Fri Dec 03 00:00:00 EST 2010
Estrogen regulation of thrombospondin-1 in human breast cancer cells.
International journal of cancer
Hyder SM,Liang Y,Wu J
MA5-13385 was used in western blot to study the regulation of thrombospondin-1 expression by estrogen in human breast cancer cells
Tue Sep 01 00:00:00 EDT 2009
Regulation of thrombospondin-1 by natural and synthetic progestins in human breast cancer cells.
Endocrine-related cancer
Hyder SM,Liang Y,Wu J,Welbern V
MA5-13385 was used in western blot to study the regulation of thrombospondin-1 expression by natural and synthetic progestins in human breast cancer cells
Tue Sep 01 00:00:00 EDT 2009
Improved vascular engraftment and graft function after inhibition of the angiostatic factor thrombospondin-1 in mouse pancreatic islets.
Diabetes
Olerud J,Johansson M,Lawler J,Welsh N,Carlsson PO
MA5-13385 was used in western blot to study the effect thrombospondin-1 inhibition on vascular engraftment and graft function in mouse pancreatic islets
Tue Jul 01 00:00:00 EDT 2008
Meteorin regulates angiogenesis at the gliovascular interface.
Glia
Park JA,Lee HS,Ko KJ,Park SY,Kim JH,Choe G,Kweon HS,Song HS,Ahn JC,Yu YS,Kim KW
MA5-13385 was used in western blot to investigate the role of meteorin in angiogenesis at the gliovascular interface
Fri Feb 01 00:00:00 EST 2008
The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer.
International journal of cancer
Rojas A,Meherem S,Kim YH,Washington MK,Willis JE,Markowitz SD,Grady WM
MA5-13385 was used in immunohistochemistry and western blot to study the effect of aberrant methylation of thrombospondin-1 on TGF-beta1 activation in colorectal cancer
Tue Jul 01 00:00:00 EDT 2008
Extracellular matrix retention of thrombospondin 1 is controlled by its conserved C-terminal region.
Journal of cell science
Adams JC,Bentley AA,Kvansakul M,Hatherley D,Hohenester E
MA5-13385 was used in immunocytochemistry to examine the role of thrombospondin 1 C-terminal region in its retention in the extracellular matrix
Sat Mar 15 00:00:00 EDT 2008
Cell type-specific post-transcriptional regulation of production of the potent antiangiogenic and proatherogenic protein thrombospondin-1 by high glucose.
The Journal of biological chemistry
Bhattacharyya S,Marinic TE,Krukovets I,Hoppe G,Stenina OI
MA5-13385 was used in immunohistochemistry to study the cell type-specific regulation of production of thrombospondin-1 by high glucose
Fri Feb 29 00:00:00 EST 2008
Dendritic cell type determines the mechanism of bystander suppression by adaptive T regulatory cells specific for the minor antigen HA-1.
Journal of immunology (Baltimore, Md. : 1950)
Derks RA,Jankowska-Gan E,Xu Q,Burlingham WJ
MA5-13385 was used in blocking or activating experiment to study the mechanism of bystander suppression by donor antigen-specific T regulatory cells in patients with organ transplant tolerance
Sat Sep 15 00:00:00 EDT 2007
Differential regulation of thrombospondin-1 expression and antiangiogenesis of ECV304 cells by trichostatin A and helixor A.
Anti-cancer drugs
Hong S,Chang SY,Yeom DH,Kang JH,Hong KJ
MA5-13385 was used in blocking or activating experiment to study the differential regulation of thrombospondin-1 expression and antiangiogenesis by trichostatin A and helixor A in ECV304 cells
Mon Oct 01 00:00:00 EDT 2007
LTBP-1 blockade in dioxin receptor-null mouse embryo fibroblasts decreases TGF-beta activity: Role of extracellular proteases plasmin and elastase.
Journal of cellular biochemistry
Gomez-Duran A,Mulero-Navarro S,Chang X,Fernandez-Salguero PM
MA5-13385 was used in western blot to study the mechanisms by which LTBP-1 blockade in dioxin receptor-null mouse embryo fibroblasts decreases TGF-beta activity
Wed Feb 01 00:00:00 EST 2006
Requirement of VPS33B, a member of the Sec1/Munc18 protein family, in megakaryocyte and platelet alpha-granule biogenesis.
Blood
Lo B,Li L,Gissen P,Christensen H,McKiernan PJ,Ye C,Abdelhaleem M,Hayes JA,Williams MD,Chitayat D,Kahr WH
MA5-13385 was used in western blot to study the role of VPS33B in megakaryocyte and platelet alpha-granule biogenesis
Thu Dec 15 00:00:00 EST 2005
Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling.
Proceedings of the National Academy of Sciences of the United States of America
Olson LE,Zhang J,Taylor H,Rose DW,Rosenfeld MG
MA5-13385 was used in immunohistochemistry to study the mechanism by which Barx regulates the remodeling of hair follicles
Tue Mar 08 00:00:00 EST 2005
Integrin alpha(v)beta8-mediated activation of transforming growth factor-beta by perivascular astrocytes: an angiogenic control switch.
The American journal of pathology
Cambier S,Gline S,Mu D,Collins R,Araya J,Dolganov G,Einheber S,Boudreau N,Nishimura SL
MA5-13385 was used in western blot to study the molecular mechanisms underlying astrocytic-endothelial paracrine signaling
Wed Jun 01 00:00:00 EDT 2005
Disruption of anterior segment development by TGF-beta1 overexpression in the eyes of transgenic mice.
Developmental dynamics : an official publication of the American Association of Anatomists
Flügel-Koch C,Ohlmann A,Piatigorsky J,Tamm ER
MA5-13385 was used in immunohistochemistry to study the role of TGF-beta1 overexpression in anterior segment development in the eyes of transgenic mice
Tue Oct 01 00:00:00 EDT 2002
Mechanism of interaction of thrombospondin with human endothelium and inhibition of sickle erythrocyte adhesion to human endothelial cells by heparin.
Biochimica et biophysica acta
Gupta K,Gupta P,Solovey A,Hebbel RP
MA5-13385 was used in blocking or activating experiment to study the mechanism by which thrombospondin mediates the adhesion of sickle erythrocytes to endothelium
Wed Jan 06 00:00:00 EST 1999