|Tested species reactivity||Protozoa|
|Published species reactivity||Protozoa|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Intact Toxoplasma gondii|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:25-1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 3 publications below|
PA5-16638 targets Toxoplasma Gondii in IHC (P) applications and shows reactivity with Human samples.
The PA5-16638 immunogen is intact Toxoplasma gondii.
Toxoplasma is a crescent shaped sporozoan that lives as intracellular parasite in various tissues of vertebrates and completes its life cycle in a single host. It is transmitted via raw/undercooked meat, contaminated soil, or by direct contact. Infection due to Toxoplasma gondii usually occurs in pregnant women where a variable degree of immunosuppression may exist or in patients receiving immunosuppressive drug therapy following organ transplant. Toxoplasma infects tissue of the GI tract where an active infection is accompanied by fever and enlargement of the spleen. Symptoms of toxoplasmosis are generally mild but severe infection of lymph nodes may occur. Congenital toxoplasmosis, in which the maternal infection is transmitted during pregnancy, can produce blindness or mental retardation in the newborn.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Acute fatal toxoplasmosis in a Great Spotted Woodpecker (Dendrocopos major).
PA5-16638 was used in immunohistochemistry to report on a case of acute fatal toxoplasmosis in a Great Spotted Woodpecker
|Jokelainen P,Vikøren T||Journal of wildlife diseases (50:117)||2014|
Immunohistochemical identification of Toxoplasma gondii in tissues from Modified Agglutination Test positive sheep.
PA5-16638 was used in immunohistochemistry to identify Toxoplasma gondii in various tissues of MAT-positive sheep using immunohistochemical methods
|Silva AF,Oliveira FC,Leite JS,Mello MF,Brandão FZ,Leite RI,Frazão-Teixeira E,Lilenbaum W,Fonseca AB,Ferreira AM||Veterinary parasitology (191:347)||2013|
Neosporosis in a captive Parma wallaby (Macropus parma).
PA5-16638 was used in immunohistochemistry to report on a case of fatal Neurospora caninum infection in a captive Parma wallaby
|Cronstedt-Fell A,Richter B,Voracek T,Kübber-Heiss A||Journal of comparative pathology (146:274)||2012|