Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (84%), Pig (98%), Rabbit (99%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
TPM2 (tropomyosin 2) is beta-tropomyosin, an isoform of tropomyosin that is mainly expressed in slow, type 1 muscle fibers. TPM2 binds to actin filaments in muscle and non-muscle cells. Plays a central role in association with the troponin complex in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. Mutations in this gene can cause nemaline myopathy 4, arthrogryposis dital 1A/2B, and cap myopathy 2.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Beta-tropomyosin; epididymis secretory protein Li 273; nemaline myopathy type 4; RP11-112J3.4; tropomyosin; Tropomyosin beta chain; Tropomyosin-2
Gene Aliases: AMCD1; DA1; DA2B; HEL-S-273; NEM4; TMSB; TPM2
UniProt ID: (Human) P07951
Entrez Gene ID: (Human) 7169
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