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Product Details
CF810089
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI2G7
Immunogen
Full length human recombinant protein of human UROD produced in HEK293T cell.
Conjugate
Unconjugated
Form
lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: UPD; URO D; Uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase
Gene Aliases: PCT; UPD; UROD
UniProt ID: (Human) P06132
Entrez Gene ID: (Human) 7389
Molecular Function:
methyltransferase
liver development
protoporphyrinogen IX biosynthetic process
heme biosynthetic process
response to iron ion
response to amine
response to estradiol
response to ethanol
uroporphyrinogen III metabolic process
response to mercury ion
response to methylmercury
response to fungicide
cellular response to arsenic-containing substance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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