MA5-15511 targets WNT5A in IHC and WB applications and shows reactivity with Human samples.
The MA5-15511 immunogen is purified recombinant fragment of WNT5A expressed in E. Coli.
MA5-15511 detects WNT5A which has a predicted molecular weight of approximately 42.3kDa.
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.
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Protein Aliases: hWNT5A; Protein Wnt-5a; wingless-type MMTV integration site family member 5A; wingless-type MMTV integration site family, member 5A; WNT-5A protein; WNT5A
Gene Aliases: hWNT5A; WNT5A
UniProt ID: (Human) P41221
Entrez Gene ID: (Human) 7474
Molecular Function: signaling molecule