|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||Assay dependent|
|Tested Species reactivity||Bacteria|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified F1 antigen from Y. pestis vaccine strain EB|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage conditions||4° C|
MA1-23074 detects Yersinia pestis F1 antigen in Bacteria samples.
MA1-23074 has been successfully used in ELISA and Western Blot procedures.
MA1-23074 immunogen corresponds to Purified F1 antigen from Y. pestis vaccine strain EB.
Yersinia pestis is a gram-negative coccobacillus belonging to the Enterobacteriaceae. Yersinia pestis is primarily a rodent pathogen, with humans being an accidental host when bitten by an infected rat flea. The flea draws viable Y. pestis organisms into its intestinal tract. Some Y. pestis in the flea are then regurgitated when the flea gets its blood meal thus transferring the infection to a new host. While growing in the flea, Y. pestis loses its capsular layer, which is made of the F1 (or fraction 1) capsule antigen. Most of the organisms are phagocytosed and killed by the polymorphonuclear leukocytes in the human host. A few bacilli are taken up by tissue macrophages. The macrophages are unable to kill Y. pestis and provide a protected environment for the organisms to synthesize their virulence factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bubonic Plague; Pasturella pestis
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.