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ZBTB17 Antibody (CF811542) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ZBTB17 (RC216143, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-ZBTB1. Positive lysates LY401167 (100 µg) and LC401167 (20 µg) can be purchased separately from OriGene.
Product Details
CF811542
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI8A7
Immunogen
Human recombinant protein fragment corresponding to amino acids 112-457 of human ZBTB17 produced in E.coli.
Conjugate
Unconjugated
Form
lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind to the promoters of adenovirus major late protein and cyclin D1 and activate transcription. Required for early embryonic development during gastrulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Miz-1; Myc-interacting zinc finger protein 1; Myc-interacting Zn finger protein-1; Zinc finger and BTB domain-containing protein 17; Zinc finger protein 151; zinc finger protein 151 (pHZ-67); Zinc finger protein 60
Gene Aliases: MIZ-1; MIZ1; pHZ-67; ZBTB17; ZNF151; ZNF60
UniProt ID: (Human) Q13105
Entrez Gene ID: (Human) 7709
Molecular Function:
C2H2 zinc finger transcription factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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