Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: early B-cell factor associated zinc finger protein; hOAZ; OLF-1/EBF associated zinc finger; Olf1/EBF-associated zinc finger protein; Smad- and Olf-interacting zinc finger protein; Zinc finger protein 423
Gene Aliases: Ebfaz; hOAZ; JBTS19; KIAA0760; NPHP14; OAZ; Roaz; Zfp104; ZFP423; ZNF423
UniProt ID: (Human) Q2M1K9
Entrez Gene ID: (Human) 23090
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support