|Tested species reactivity||Many|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide.|
|Storage buffer||PBS, pH 7.4|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 1 publications below|
This antibody recognizes the C-terminal peptide sequence ESESQGPK (aa 441-448) of neuron-specific human beta III-tubulin.
Tubulin is a heterodimer consisting of alpha and beta-tubulin subunits. It is nearly ubiquitous among eukaryotic cells. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules. This intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Novel crystalloid oligodendrogliopathy in hereditary spastic paraplegia.
MA1-19582 was used in immunohistochemistry to study crystalloid oligodendrogliopathy in hereditary spastic paraplegia
|Woehrer A,Laszlo L,Finsterer J,Stöllberger C,Furtner J,Rinner W,Molnar K,Budka H,Kovacs GG||Acta neuropathologica (124:583)||2012|