|Tested species reactivity||Human, Non-human primate|
|Published species reactivity||Bovine, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 9-40 amino acids from the N-terminal region of human c-KIT|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:10-1:50|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 3 publications below|
KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gastrointestinal stromal tumours in children and young adults: a clinicopathologic series with long-term follow-up from the database of the Cooperative Weichteilsarkom Studiengruppe (CWS).
PA5-14694 was used in immunohistochemistry to investigate gastrointestinal stromal tumours in patients with long-term follow-up
|Benesch M,Leuschner I,Wardelmann E,Thielen M,Schmid I,Kontny U,Ebetsberger G,Frey E,Graf N,Schneider DT,Kremens B,Amann G,Urban C,Schlemmer M,Quehenberger F,Klingebiel T,Dantonello T,Koscielniak E||European journal of cancer (Oxford, England : 1990) (47:1692)||2011|
Primary malignant deciduoid peritoneal mesothelioma: a report of the cytohistological and immunohistochemical appearances.
PA5-14694 was used in immunohistochemistry to investigate deciduoid features of malignant mesothelioma by histomorphological and immunohistochemical evaluation
|Ustun H,Astarci HM,Sungu N,Ozdemir A,Ekinci C||Diagnostic cytopathology (39:402)||2011|
Development and practical applications of a method for repeated transvaginal, ultrasound-guided biopsy collection of the bovine ovary.
PA5-14694 was used in immunohistochemistry to develop a method for transvaginal ultrasound-guided biopsy collection of the bovine ovary
|Aerts JM,Oste M,Bols PE||Theriogenology (64:947)||2005|