Product References
Wild‑type IDH1 affects cell migration by modulating the PI3K/AKT/mTOR pathway in primary glioblastoma cells.
Molecular medicine reports
Shen X,Wu S,Zhang J,Li M,Xu F,Wang A,Lei Y,Zhu G
A-21280 was used in Western Blotting to explore the mechanisms governing IDH1's control of glioblastoma cell migration.
Tue Sep 01 00:00:00 EDT 2020
MYC Amplification as a Predictive Factor of Complete Pathologic Response to Docetaxel-based Neoadjuvant Chemotherapy for Breast Cancer.
Clinical breast cancer
Pereira CBL,Leal MF,Abdelhay ESFW,Demachki S,Assumpção PP,de Souza MC,Moreira-Nunes CA,Tanaka AMDS,Smith MC,Burbano RR
A-21280 was used in immunohistochemistry to identify biomarkers to use for patients receiving neoadjuvant chemotherapy to treat breast cancer
Thu Jun 01 00:00:00 EDT 2017
A non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis through PCM1 phosphorylation.
EMBO reports
Hori A,Barnouin K,Snijders AP,Toda T
A-21280 was used in immunocytochemistry to assess PCM1 phosphorylation as a non-canonical function of Plk4 in centriolar satellite integrity and ciliogenesis
Tue Mar 01 00:00:00 EST 2016
Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide.
The Journal of biological chemistry
Lee CC,Julian MC,Tiller KE,Meng F,DuConge SE,Akter R,Raleigh DP,Tessier PM
A-21280 was used in flow cytometry to characterize the design of anti-amyloid domain antibodies specific for beta-amyloid and islet amyloid polpeptides
Fri Feb 05 00:00:00 EST 2016
The DRBD13 RNA binding protein is involved in the insect-stage differentiation process of Trypanosoma brucei.
FEBS letters
Jha BA,Gazestani VH,Yip CW,Salavati R
A-21280 was used in western blot to study the DRBD13 in trypanosomes.
Wed Jul 08 00:00:00 EDT 2015
Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies.
Protein engineering, design & selection : PEDS
Julian MC,Lee CC,Tiller KE,Rabia LA,Day EK,Schick AJ,Tessier PM
A-21280 was used in flow cytometry to discuss how to improve the binding affinity of a lead VH domain grafted with Aβ residues 33-42 in CDR3.
Thu Oct 01 00:00:00 EDT 2015
MYC overexpression and poor prognosis in sporadic breast cancer with BRCA1 deficiency.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
Ren J,Jin F,Yu Z,Zhao L,Wang L,Bai X,Zhao H,Yao W,Mi X,Wang E,Olopade OI,Wei M
A-21280 was used in immunohistochemistry (paraffin) to study BRAC1-deficiency in sporadic breast cancer.
Sun Dec 01 00:00:00 EST 2013
Prognostic and predictive significance of MYC and KRAS alterations in breast cancer from women treated with neoadjuvant chemotherapy.
PloS one
Pereira CB,Leal MF,de Souza CR,Montenegro RC,Rey JA,Carvalho AA,Assumpção PP,Khayat AS,Pinto GR,Demachki S,de Arruda Cardoso Smith M,Burbano RR
A-21280 was used in immunohistochemistry (paraffin) to investigate prognostic or predictive biomarkers of breast cancer.
Tue Sep 24 00:00:00 EDT 2013
Novel MeCP2 isoform-specific antibody reveals the endogenous MeCP2E1 expression in murine brain, primary neurons and astrocytes.
PloS one
Zachariah RM,Olson CO,Ezeonwuka C,Rastegar M
Published figure using c-Myc monoclonal antibody (Product # A-21280) in Immunofluorescence
Thu May 30 00:00:00 EDT 2013
A lipid receptor sorts polyomavirus from the endolysosome to the endoplasmic reticulum to cause infection.
PLoS pathogens
Qian M,Cai D,Verhey KJ,Tsai B
A-21280 was used in immunocytochemistry to study how the murine polyomavirus reaches the endoplasmic reticulum
Mon Jun 01 00:00:00 EDT 2009
MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy.
PloS one
Rastegar M,Hotta A,Pasceri P,Makarem M,Cheung AY,Elliott S,Park KJ,Adachi M,Jones FS,Clarke ID,Dirks P,Ellis J
Published figure using c-Myc monoclonal antibody (Product # A-21280) in Immunofluorescence
Thu Aug 27 00:00:00 EDT 2009
MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy.
PloS one
Rastegar M,Hotta A,Pasceri P,Makarem M,Cheung AY,Elliott S,Park KJ,Adachi M,Jones FS,Clarke ID,Dirks P,Ellis J
Published figure using c-Myc monoclonal antibody (Product # A-21280) in Immunofluorescence
Thu Aug 27 00:00:00 EDT 2009
Functional protein delivery into neurons using polymeric nanoparticles.
The Journal of biological chemistry
Hasadsri L,Kreuter J,Hattori H,Iwasaki T,George JM
A-21280 was used in immunocytochemistry and western blot to use polybutylcyanoacrylate nanoparticles to introduce functional proteins into neurons and neuronal cell lines
Fri Mar 13 00:00:00 EDT 2009
Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation.
Genes & development
Deng Y,Singer RH,Gu W
Published figure using c-Myc monoclonal antibody (Product # A-21280) in Western Blot
Tue Apr 15 00:00:00 EDT 2008
Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting.
The Journal of biological chemistry
Baumeister MA,Martinu L,Rossman KL,Sondek J,Lemmon MA,Chou MM
A-21280 was used in immunocytochemistry to study the functional relevance of low affinity phosphoinositide binding to pleckstrin homology domains
Fri Mar 28 00:00:00 EST 2003
Sphingosine-1-phosphate phosphohydrolase in regulation of sphingolipid metabolism and apoptosis.
The Journal of cell biology
Le Stunff H,Galve-Roperh I,Peterson C,Milstien S,Spiegel S
A-21280 was used in immunocytochemistry and western blot to investigate the functions of SPP-1 in sphingolipid biosynthesis
Mon Sep 16 00:00:00 EDT 2002
TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2.
The Journal of cell biology
Hayes S,Chawla A,Corvera S
A-21280 was used in immunocytochemistry to study TGF beta receptor trafficking
Mon Sep 30 00:00:00 EDT 2002
Easily reversible desthiobiotin binding to streptavidin, avidin, and other biotin-binding proteins: uses for protein labeling, detection, and isolation.
Analytical biochemistry
Hirsch JD,Eslamizar L,Filanoski BJ,Malekzadeh N,Haugland RP,Beechem JM,Haugland RP
A-21280 was used in western blot to assess desthiobiotin-based reagents as replacement for biotin-based reagents.
Sun Sep 15 00:00:00 EDT 2002
The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein.
The Journal of biological chemistry
Xu X,Shi YC,Gao W,Mao G,Zhao G,Agrawal S,Chisolm GM,Sui D,Cui MZ
A-21280 was used in immunoprecipitation and western blot to elucidate how presenilin-associated protein regulates cell death
Fri Dec 13 00:00:00 EST 2002
Oligomerization, F-actin interaction, and membrane association of the ubiquitous mammalian coronin 3 are mediated by its carboxyl terminus.
The Journal of biological chemistry
Spoerl Z,Stumpf M,Noegel AA,Hasse A
A-21280 was used in immunocytochemistry to study coronin 3 oligomerization
Fri Dec 13 00:00:00 EST 2002
Rer1p, a retrieval receptor for endoplasmic reticulum membrane proteins, is dynamically localized to the Golgi apparatus by coatomer.
The Journal of cell biology
Sato K,Sato M,Nakano A
A-21280 was used in immunocytochemistry to study Rer1p-mediated protein trafficking
Mon Mar 05 00:00:00 EST 2001
Signaling complexes of the FERM domain-containing protein GRSP1 bound to ARF exchange factor GRP1.
The Journal of biological chemistry
Klarlund JK,Holik J,Chawla A,Park JG,Buxton J,Czech MP
A-21280 was used in immunocytochemistry to assess the binding to ARF exchange factor GRP1 by signaling complexes of the FERM domain-containing protein GRSP1
Fri Oct 26 00:00:00 EDT 2001