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PA5-19601 targets eIF2B epsilon in IF and WB applications and shows reactivity with Human, mouse, and Rat samples.
The PA5-19601 immunogen is synthetic peptide conjugated to KLH derived from within residues 550 - 650 of Human eIF2B epsilon.
PA5-19601 detects eIF2B epsilon which has a predicted molecular weight of approximately 75 kDa.
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B, a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
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