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Recommended positive controls: human kidney.
Predicted reactivity: Cow: 92%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Mouse: 100%; Rabbit: 100%; Rat: 100%.
Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis. L-Myc gene ontology annotations include DNA binding function, DNA-binding transcription factor activity, RNA polymerase II-specific action, protein dimerization activity, and regulation of inner ear auditory receptor cell differentiation.
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